General Information of the Compound
Compound ID
CP0435556
Compound Name
2-(2,3-dihydro-1H-inden-5-yloxy)-N-(5-phenyl-1H-1,2,4-triazol-3-yl)acetamide
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Structure
Formula
C19H18N4O2
Molecular Weight
334.379
Canonical SMILES
O=C(COc1ccc2CCCc2c1)Nc1nnc([nH]1)-c1ccccc1
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InChI
InChI=1S/C19H18N4O2/c24-17(12-25-16-10-9-13-7-4-8-15(13)11-16)20-19-21-18(22-23-19)14-5-2-1-3-6-14/h1-3,5-6,9-11H,4,7-8,12H2,(H2,20,21,22,23,24)
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InChIKey
VABPMXNJLMPQNR-UHFFFAOYSA-N
Physicochemical Property
logP
2.9779
Rotatable Bonds
5
Heavy Atom Count
25
Polar Areas
79.9
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 32459103
ChEMBL ID
CHEMBL2151260
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 3900 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2200 nM
   TI
   LI
   LO
   TS