General Information of the Compound
Compound ID
CP0435555
Compound Name
4-chloro-N-(5-phenyl-1H-1,2,4-triazol-3-yl)benzamide
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Structure
Formula
C15H11ClN4O
Molecular Weight
298.733
Canonical SMILES
Clc1ccc(cc1)C(=O)Nc1nnc([nH]1)-c1ccccc1
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InChI
InChI=1S/C15H11ClN4O/c16-12-8-6-11(7-9-12)14(21)18-15-17-13(19-20-15)10-4-2-1-3-5-10/h1-9H,(H2,17,18,19,20,21)
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InChIKey
OSWPTXKPJKLFMB-UHFFFAOYSA-N
Physicochemical Property
logP
3.3774
Rotatable Bonds
3
Heavy Atom Count
21
Polar Areas
70.67
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
21

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 17500622
ChEMBL ID
CHEMBL2151130
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 2800 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 200 nM
   TI
   LI
   LO
   TS