General Information of the Compound
Compound ID
CP0435039
Compound Name
2-(2,6-diethylphenyl)-N-ethyl-N-naphthalen-1-yl-4-phenylmethoxy-5,6,7,8-tetrahydroquinolin-5-amine
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Structure
Formula
C38H40N2O
Molecular Weight
540.751
Canonical SMILES
CCN(C1CCCc2nc(cc(OCc3ccccc3)c12)-c1c(CC)cccc1CC)c1cccc2ccccc12
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InChI
InChI=1S/C38H40N2O/c1-4-28-18-12-19-29(5-2)37(28)33-25-36(41-26-27-15-8-7-9-16-27)38-32(39-33)22-14-24-35(38)40(6-3)34-23-13-20-30-17-10-11-21-31(30)34/h7-13,15-21,23,25,35H,4-6,14,22,24,26H2,1-3H3
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InChIKey
FFAFHWRQQVVOGU-UHFFFAOYSA-N
Physicochemical Property
logP
9.5095
Rotatable Bonds
9
Heavy Atom Count
41
Polar Areas
25.36
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
41

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 25192335
SID: 57301000
ChEMBL ID
CHEMBL259713
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02772, C5a anaphylatoxin chemotactic receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 = 270 nM
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