General Information of the Compound
Compound ID
CP0434025
Compound Name
N-[[2-[4-[[2-(dimethylamino)ethyl-methylamino]methyl]phenyl]phenyl]methyl]-N-(3-methoxypropyl)-2-phenylacetamide
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Structure
Formula
C31H41N3O2
Molecular Weight
487.688
Canonical SMILES
COCCCN(Cc1ccccc1-c1ccc(CN(C)CCN(C)C)cc1)C(=O)Cc1ccccc1
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InChI
InChI=1S/C31H41N3O2/c1-32(2)20-21-33(3)24-27-15-17-28(18-16-27)30-14-9-8-13-29(30)25-34(19-10-22-36-4)31(35)23-26-11-6-5-7-12-26/h5-9,11-18H,10,19-25H2,1-4H3
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InChIKey
VENNTGAOEMSNFB-UHFFFAOYSA-N
Physicochemical Property
logP
4.9548
Rotatable Bonds
14
Heavy Atom Count
36
Polar Areas
36.02
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44572092
ChEMBL ID
CHEMBL475380
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01121, Motilin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 3162.28 nM
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