General Information of the Compound
Compound ID
CP0434001
Compound Name
N-[(1Z)-1-benzylidene-3-[2-(dimethylamino)ethyl]-2-methylinden-5-yl]naphthalene-2-sulfonamide
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Structure
Formula
C31H30N2O2S
Molecular Weight
494.66
Canonical SMILES
CN(C)CCC1=C(C)\C(=C\c2ccccc2)c2ccc(NS(=O)(=O)c3ccc4ccccc4c3)cc12
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InChI
InChI=1S/C31H30N2O2S/c1-22-28(17-18-33(2)3)31-21-26(14-16-29(31)30(22)19-23-9-5-4-6-10-23)32-36(34,35)27-15-13-24-11-7-8-12-25(24)20-27/h4-16,19-21,32H,17-18H2,1-3H3/b30-19-
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InChIKey
KRAFDWDSBDERGJ-FSGOGVSDSA-N
Physicochemical Property
logP
6.92
Rotatable Bonds
7
Heavy Atom Count
36
Polar Areas
49.41
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 16718826
SID: 26672897
ChEMBL ID
CHEMBL457569
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 216 nM
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