General Information of the Compound
Compound ID
CP0433302
Compound Name
N,N-dimethyl-5-[3-[(E)-(4-methylpiperazin-1-yl)iminomethyl]-2-phenylindol-1-yl]sulfonylnaphthalen-1-amine
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Structure
Formula
C32H33N5O2S
Molecular Weight
551.716
Canonical SMILES
CN(C)c1cccc2c(cccc12)S(=O)(=O)n1c(c(\C=N\N2CCN(C)CC2)c2ccccc12)-c1ccccc1
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InChI
InChI=1S/C32H33N5O2S/c1-34(2)29-17-9-15-27-25(29)14-10-18-31(27)40(38,39)37-30-16-8-7-13-26(30)28(32(37)24-11-5-4-6-12-24)23-33-36-21-19-35(3)20-22-36/h4-18,23H,19-22H2,1-3H3/b33-23+
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InChIKey
QXWPFTKGGUFTQA-GZZLJNBRSA-N
Physicochemical Property
logP
5.3458
Rotatable Bonds
6
Heavy Atom Count
40
Polar Areas
61.15
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
7
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 71769424
ChEMBL ID
CHEMBL2414704
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 1400 nM
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