General Information of the Compound
Compound ID
CP0431674
Compound Name
CHEMBL4594096
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Formula
C29H47N7O
Molecular Weight
509.743
Canonical SMILES
CC(C)[C@H]1CC[C@H](CC1)N1CCC(CC1)n1cc(CNC(=O)[C@@H](N)CCCNC(N)=N)c2ccccc12
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InChI
InChI=1S/C29H47N7O/c1-20(2)21-9-11-23(12-10-21)35-16-13-24(14-17-35)36-19-22(25-6-3-4-8-27(25)36)18-34-28(37)26(30)7-5-15-33-29(31)32/h3-4,6,8,19-21,23-24,26H,5,7,9-18,30H2,1-2H3,(H,34,37)(H4,31,32,33)/t21-,23+,26-/m0/s1
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InChIKey
WLQVWCBBPYAMOQ-SYVJQLTCSA-N
Physicochemical Property
logP
3.69977
Rotatable Bonds
10
Heavy Atom Count
37
Polar Areas
125.19
Hydrogen Bond Donor Count
5
Hydrogen Bond Acceptor Count
5
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4594096
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01200, Delta-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT00983, Kappa-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 674 nM
   TI
   LI
   LO
   TS
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 857 nM
   TI
   LI
   LO
   TS
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
Ki = 11 nM
   TI
   LI
   LO
   TS