General Information of the Compound
Compound ID
CP0431571
Compound Name
CHEMBL4467156
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Formula
C25H38N4S
Molecular Weight
426.674
Canonical SMILES
CC(C)[C@H]1CC[C@H](CC1)N1CCC(CC1)n1cc(CCNC(N)=S)c2ccccc12
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InChI
InChI=1S/C25H38N4S/c1-18(2)19-7-9-21(10-8-19)28-15-12-22(13-16-28)29-17-20(11-14-27-25(26)30)23-5-3-4-6-24(23)29/h3-6,17-19,21-22H,7-16H2,1-2H3,(H3,26,27,30)/t19-,21+
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InChIKey
SDNMVMVANFPUFO-TYKWCNGQSA-N
Physicochemical Property
logP
4.8687
Rotatable Bonds
6
Heavy Atom Count
30
Polar Areas
46.22
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4467156
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01200, Delta-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT00983, Kappa-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 81 nM
   TI
   LI
   LO
   TS
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 227 nM
   TI
   LI
   LO
   TS
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
Ki = 24.4 nM
   TI
   LI
   LO
   TS