General Information of the Compound
Compound ID
CP0430027
Compound Name
5-[2-[[1-(4-chlorophenyl)sulfonyl-3,4-dihydro-2H-quinolin-7-yl]oxy]-6-cyclopropylpyridin-4-yl]-3-cyclopropyl-1,2,4-oxadiazole
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Structure
Formula
C28H25ClN4O4S
Molecular Weight
549.052
Canonical SMILES
Clc1ccc(cc1)S(=O)(=O)N1CCCc2ccc(Oc3cc(cc(n3)C3CC3)-c3nc(no3)C3CC3)cc12
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InChI
InChI=1S/C28H25ClN4O4S/c29-21-8-11-23(12-9-21)38(34,35)33-13-1-2-18-7-10-22(16-25(18)33)36-26-15-20(14-24(30-26)17-3-4-17)28-31-27(32-37-28)19-5-6-19/h7-12,14-17,19H,1-6,13H2
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InChIKey
BMBHHJOJERDYIV-UHFFFAOYSA-N
Physicochemical Property
logP
6.4736
Rotatable Bonds
7
Heavy Atom Count
38
Polar Areas
98.42
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
7
Complexity
38

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 76332169
ChEMBL ID
CHEMBL3112979
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02455, Glucose-dependent insulinotropic receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 130 nM
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