General Information of the Compound
Compound ID
CP0429172
Compound Name
(2S,4R)-2-amino-4-[(E)-3-(4-methylphenyl)prop-2-enyl]pentanedioic acid
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Structure
Formula
C15H19NO4
Molecular Weight
277.32
Canonical SMILES
Cc1ccc(\C=C\C[C@H](C[C@H](N)C(O)=O)C(O)=O)cc1
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InChI
InChI=1S/C15H19NO4/c1-10-5-7-11(8-6-10)3-2-4-12(14(17)18)9-13(16)15(19)20/h2-3,5-8,12-13H,4,9,16H2,1H3,(H,17,18)(H,19,20)/b3-2+/t12-,13+/m1/s1
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InChIKey
XTGCHIIKJWMWQR-XDYXTIEYSA-N
Physicochemical Property
logP
1.90112
Rotatable Bonds
7
Heavy Atom Count
20
Polar Areas
100.62
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Complexity
20

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10778899
SID: 15817209
ChEMBL ID
CHEMBL292745
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01518, Glutamate receptor ionotropic, kainate 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 172 nM
   TI
   LI
   LO
   TS
Protein ID: PT02754, Glutamate receptor ionotropic, kainate 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 4375 nM
   TI
   LI
   LO
   TS