General Information of the Compound
Compound ID
CP0427257
Compound Name
1-((3R,6S)-6-(3-cyanophenyl)bicyclo[4.1.0]heptan-3-yl)-3-(4-fluoro-3-(trifluoromethyl)phenyl)-1-(2-(1-(methylsulfonyl)piperidin-4-yl)ethyl)urea
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Structure
Formula
C30H34F4N4O3S
Molecular Weight
606.686
Canonical SMILES
CS(=O)(=O)N1CCC(CCN([C@@H]2CC[C@@]3(CC3C2)c2cccc(c2)C#N)C(=O)Nc2ccc(F)c(c2)C(F)(F)F)CC1
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InChI
InChI=1S/C30H34F4N4O3S/c1-42(40,41)37-12-8-20(9-13-37)10-14-38(28(39)36-24-5-6-27(31)26(17-24)30(32,33)34)25-7-11-29(18-23(29)16-25)22-4-2-3-21(15-22)19-35/h2-6,15,17,20,23,25H,7-14,16,18H2,1H3,(H,36,39)/t23?,25-,29-/m1/s1
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InChIKey
TURPWDNGSKAUDF-NXRLCEILSA-N
Physicochemical Property
logP
6.12218
Rotatable Bonds
7
Heavy Atom Count
42
Polar Areas
93.51
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44424235
ChEMBL ID
CHEMBL228289
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01027, Melanin-concentrating hormone receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 80 nM
   TI
   LI
   LO
   TS