General Information of the Compound
Compound ID
CP0425864
Compound Name
2-Propylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5'-monophosphate
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Structure
Formula
C12H19N2O8PS
Molecular Weight
382.331
Canonical SMILES
CCCSc1nc(=O)ccn1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O
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InChI
InChI=1S/C12H19N2O8PS/c1-2-5-24-12-13-8(15)3-4-14(12)11-10(17)9(16)7(22-11)6-21-23(18,19)20/h3-4,7,9-11,16-17H,2,5-6H2,1H3,(H2,18,19,20)/t7-,9-,10-,11-/m1/s1
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InChIKey
FENPKUDFWRAYIO-QCNRFFRDSA-N
Physicochemical Property
logP
-0.5261
Rotatable Bonds
7
Heavy Atom Count
24
Polar Areas
151.34
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
9
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 52952396
SID: 123104005
ChEMBL ID
CHEMBL1767419
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04714, P2Y purinoceptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
EC50 = 4800 nM
   TI
   LI
   LO
   TS
Protein ID: PT05219, P2Y purinoceptor 4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
Protein ID: PT02796, P2Y purinoceptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
EC50 = 6200 nM
   TI
   LI
   LO
   TS