General Information of the Compound
Compound ID
CP0424758
Compound Name
2-(benzyloxy)-5-(4-methylpiperazin-1-yl)-N-phenethylbenzenamine
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Structure
Formula
C26H31N3O
Molecular Weight
401.554
Canonical SMILES
CN1CCN(CC1)c1ccc(OCc2ccccc2)c(NCCc2ccccc2)c1
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InChI
InChI=1S/C26H31N3O/c1-28-16-18-29(19-17-28)24-12-13-26(30-21-23-10-6-3-7-11-23)25(20-24)27-15-14-22-8-4-2-5-9-22/h2-13,20,27H,14-19,21H2,1H3
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InChIKey
QFZMKTVOJUEHMG-UHFFFAOYSA-N
Physicochemical Property
logP
4.672
Rotatable Bonds
8
Heavy Atom Count
30
Polar Areas
27.74
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11661320
SID: 16764992
ChEMBL ID
CHEMBL249196
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 1284 nM
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