General Information of the Compound
Compound ID
CP0416705
Compound Name
ethyl (2R)-2-[[[(E)-5-hydroxy-4-methylpent-3-enyl]-phenoxyphosphoryl]amino]propanoate
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Structure
Formula
C17H26NO5P
Molecular Weight
355.371
Canonical SMILES
CCOC(=O)[C@@H](C)N[P@](=O)(CC\C=C(/C)CO)Oc1ccccc1
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InChI
InChI=1S/C17H26NO5P/c1-4-22-17(20)15(3)18-24(21,12-8-9-14(2)13-19)23-16-10-6-5-7-11-16/h5-7,9-11,15,19H,4,8,12-13H2,1-3H3,(H,18,21)/b14-9+/t15-,24+/m1/s1
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InChIKey
YGSLLMNEAQXTQJ-VYBGJCFVSA-N
Physicochemical Property
logP
3.1284
Rotatable Bonds
10
Heavy Atom Count
24
Polar Areas
84.86
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 155536606
ChEMBL ID
CHEMBL4473949
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06506, Butyrophilin subfamily 3 member A1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000002 K-562 Homo sapiens (Human)  3
1
EC50 = 520 nM
   TI
   LI
   LO
   TS
2
EC50 = 2000 nM
   TI
   LI
   LO
   TS
3
EC50 = 6000 nM
   TI
   LI
   LO
   TS