General Information of the Compound
Compound ID
CP0415312
Compound Name
N-[3-[5-(3-nitrophenyl)-2-oxo-1H-imidazol-3-yl]phenyl]methanesulfonamide
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Structure
Formula
C16H14N4O5S
Molecular Weight
374.378
Canonical SMILES
CS(=O)(=O)Nc1cccc(c1)-n1cc([nH]c1=O)-c1cccc(c1)[N+]([O-])=O
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InChI
InChI=1S/C16H14N4O5S/c1-26(24,25)18-12-5-3-6-13(9-12)19-10-15(17-16(19)21)11-4-2-7-14(8-11)20(22)23/h2-10,18H,1H3,(H,17,21)
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InChIKey
XDCRYHZNXPVAOW-UHFFFAOYSA-N
Physicochemical Property
logP
2.1123
Rotatable Bonds
5
Heavy Atom Count
26
Polar Areas
127.1
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118735922
ChEMBL ID
CHEMBL3422822
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT05529, Transient receptor potential cation channel subfamily M member 8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 26000 nM
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