General Information of the Compound
Compound ID
CP0412518
Compound Name
2-(2,6-diethylphenyl)-5-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-4-methoxy-5,6,7,8-tetrahydroquinoline
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Structure
Formula
C31H38N2O3
Molecular Weight
486.656
Canonical SMILES
CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)N1CCc2cc(OC)c(OC)cc2C1
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InChI
InChI=1S/C31H38N2O3/c1-6-20-10-8-11-21(7-2)30(20)25-18-29(36-5)31-24(32-25)12-9-13-26(31)33-15-14-22-16-27(34-3)28(35-4)17-23(22)19-33/h8,10-11,16-18,26H,6-7,9,12-15,19H2,1-5H3
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InChIKey
ZMXMYHXDBFKTEV-UHFFFAOYSA-N
Physicochemical Property
logP
6.3349
Rotatable Bonds
7
Heavy Atom Count
36
Polar Areas
43.82
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44450458
ChEMBL ID
CHEMBL260825
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02772, C5a anaphylatoxin chemotactic receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS