General Information of the Compound
Compound ID
CP0410845
Compound Name
8,15-Dihydroxy-icosa-5,9,11,13-tetraenoic acid (2-hydroxy-ethyl)-amide
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Structure
Formula
C22H37NO4
Molecular Weight
379.541
Canonical SMILES
CCCCC[C@H](O)\C=C\C=C/C=C/[C@@H](O)C\C=C/CCCC(=O)NCCO
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InChI
InChI=1S/C22H37NO4/c1-2-3-8-13-20(25)14-9-4-5-10-15-21(26)16-11-6-7-12-17-22(27)23-18-19-24/h4-6,9-11,14-15,20-21,24-26H,2-3,7-8,12-13,16-19H2,1H3,(H,23,27)/b5-4-,11-6-,14-9+,15-10+/t20-,21+/m0/s1
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InChIKey
PYFSFMSQYCMIGN-JUSPISSWSA-N
Physicochemical Property
logP
3.1822
Rotatable Bonds
16
Heavy Atom Count
27
Polar Areas
89.79
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
4
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44347982
ChEMBL ID
CHEMBL126042
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01099, Fatty-acid amide hydrolase 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
Ki = 690 nM
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   LI
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