General Information of the Compound
Compound ID
CP0410362
Compound Name
4-[[7-[4-(trifluoromethyl)phenyl]-1-benzothiophen-2-yl]methylamino]butanoic acid
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Structure
Formula
C20H18F3NO2S
Molecular Weight
393.43
Canonical SMILES
OC(=O)CCCNCc1cc2cccc(-c3ccc(cc3)C(F)(F)F)c2s1
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InChI
InChI=1S/C20H18F3NO2S/c21-20(22,23)15-8-6-13(7-9-15)17-4-1-3-14-11-16(27-19(14)17)12-24-10-2-5-18(25)26/h1,3-4,6-9,11,24H,2,5,10,12H2,(H,25,26)
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InChIKey
RUXOXYWHXQUSCO-UHFFFAOYSA-N
Physicochemical Property
logP
5.5415
Rotatable Bonds
7
Heavy Atom Count
27
Polar Areas
49.33
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 134131363
ChEMBL ID
CHEMBL3884795
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01779, Sphingosine 1-phosphate receptor 4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 1900 nM
   TI
   LI
   LO
   TS
Protein ID: PT01780, Sphingosine 1-phosphate receptor 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 552 nM
   TI
   LI
   LO
   TS