General Information of the Compound
Compound ID
CP0407361
Compound Name
N-hydroxy-2-naphthalen-2-ylacetamide
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Synonyms
106359-52-8
2-Naphthaleneacetamide, N-hydroxy-
AC1Q7DIT
AKOS000168393
BDBM50015114
CHEMBL346935
CTK8A6801
KSC-11-264-7
KUC108662N
MCULE-5699071643
MolPort-004-327-963
N-Hydroxy-2-naphthalen-2-yl-acetamide
N-hydroxy-2-(naphthalen-2-yl)acetamide
NCGC00186600-01
NCGC00186600-02
NE14616
SCHEMBL1520280
ZINC19423737
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Structure
Formula
C12H11NO2
Molecular Weight
201.225
Canonical SMILES
ONC(=O)Cc1ccc2ccccc2c1
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InChI
InChI=1S/C12H11NO2/c14-12(13-15)8-9-5-6-10-3-1-2-4-11(10)7-9/h1-7,15H,8H2,(H,13,14)
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InChIKey
IYXUERDUKOVYLR-UHFFFAOYSA-N
Physicochemical Property
logP
1.8877
Rotatable Bonds
2
Heavy Atom Count
15
Polar Areas
49.33
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Complexity
15

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 24689999
ChEMBL ID
CHEMBL346935
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01743, Polyunsaturated fatty acid 5-lipoxygenase
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000194 RBL-1
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
IC50 = 19000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( N-Hydroxy-2-naphthalen-2-yl-acetamide )
Drug Name N-Hydroxy-2-naphthalen-2-yl-acetamide
Target(s)
Arachidonate 5-lipoxygenase (5-LOX)
 Target Info 
Inhibitor