General Information of the Compound
Compound ID
CP0405127
Compound Name
propan-2-yl 4-[2-[[2-(2,3,6-trifluorophenyl)acetyl]amino]ethyl]piperidine-1-carboxylate
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Structure
Formula
C19H25F3N2O3
Molecular Weight
386.414
Canonical SMILES
CC(C)OC(=O)N1CCC(CCNC(=O)Cc2c(F)ccc(F)c2F)CC1
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InChI
InChI=1S/C19H25F3N2O3/c1-12(2)27-19(26)24-9-6-13(7-10-24)5-8-23-17(25)11-14-15(20)3-4-16(21)18(14)22/h3-4,12-13H,5-11H2,1-2H3,(H,23,25)
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InChIKey
FKPHGZTXBXSINT-UHFFFAOYSA-N
Physicochemical Property
logP
3.4097
Rotatable Bonds
6
Heavy Atom Count
27
Polar Areas
58.64
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 53325083
ChEMBL ID
CHEMBL1684039
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02455, Glucose-dependent insulinotropic receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 409 nM
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