General Information of the Compound
Compound ID
CP0402774
Compound Name
(5S)-1-[4-(4-methoxyphenyl)butyl]-5-[(4-phenylmethoxyphenyl)methyl]-3-(2-pyrrolidin-1-ylethyl)imidazolidine-2,4-dione
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Structure
Formula
C34H41N3O4
Molecular Weight
555.719
Canonical SMILES
COc1ccc(CCCCN2[C@@H](Cc3ccc(OCc4ccccc4)cc3)C(=O)N(CCN3CCCC3)C2=O)cc1
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InChI
InChI=1S/C34H41N3O4/c1-40-30-16-12-27(13-17-30)9-5-6-22-36-32(33(38)37(34(36)39)24-23-35-20-7-8-21-35)25-28-14-18-31(19-15-28)41-26-29-10-3-2-4-11-29/h2-4,10-19,32H,5-9,20-26H2,1H3/t32-/m0/s1
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InChIKey
UPULWNSZJPTRND-YTTGMZPUSA-N
Physicochemical Property
logP
5.5682
Rotatable Bonds
14
Heavy Atom Count
41
Polar Areas
62.32
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
41

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44346106
ChEMBL ID
CHEMBL332786
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01196, Somatostatin receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 501.19 nM
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