General Information of the Compound
Compound ID
CP0401682
Compound Name
(2R)-1-(cyclopentyl(phenyl)methoxy)-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propan-2-ol
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Structure
Formula
C29H37NO2
Molecular Weight
431.62
Canonical SMILES
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COC(C1CCCC1)c1ccccc1
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InChI
InChI=1S/C29H37NO2/c1-29(2,19-22-16-17-23-10-6-9-15-26(23)18-22)30-20-27(31)21-32-28(25-13-7-8-14-25)24-11-4-3-5-12-24/h3-6,9-12,15-18,25,27-28,30-31H,7-8,13-14,19-21H2,1-2H3/t27-,28?/m1/s1
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InChIKey
UOGMGOVUGLOIKR-QXPUDEPPSA-N
Physicochemical Property
logP
6.0595
Rotatable Bonds
10
Heavy Atom Count
32
Polar Areas
41.49
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46891465
ChEMBL ID
CHEMBL1084200
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01916, Extracellular calcium-sensing receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000868 PC12 Rattus norvegicus (Rat)  1
1
IC50 = 200 nM
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