General Information of the Compound
Compound ID
CP0399607
Compound Name
3-[2-[(4-bromophenyl)methyl]-6-methylbenzimidazol-1-yl]-N,N-dimethylpropan-1-amine
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Structure
Formula
C20H24BrN3
Molecular Weight
386.337
Canonical SMILES
CN(C)CCCn1c(Cc2ccc(Br)cc2)nc2ccc(C)cc12
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InChI
InChI=1S/C20H24BrN3/c1-15-5-10-18-19(13-15)24(12-4-11-23(2)3)20(22-18)14-16-6-8-17(21)9-7-16/h5-10,13H,4,11-12,14H2,1-3H3
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InChIKey
NAZLGRPSEFDGBZ-UHFFFAOYSA-N
Physicochemical Property
logP
4.64972
Rotatable Bonds
6
Heavy Atom Count
24
Polar Areas
21.06
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44456069
ChEMBL ID
CHEMBL430033
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02118, Neuronal acetylcholine receptor subunit alpha-7
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000029 GH4C1 Rattus norvegicus (Rat)  1
1
EC50 = 1700 nM
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