General Information of the Compound
Compound ID
CP0396781
Compound Name
2-({2-cyclopentyl-4-[4-(2- methoxy-phenyl)-piperidin-1-yl]- quinazolin-6-yl}-methyl-amino)- ethanol
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Structure
Formula
C28H36N4O2
Molecular Weight
460.622
Canonical SMILES
COc1ccccc1C1CCN(CC1)c1nc(nc2ccc(cc12)N(C)CCO)C1CCCC1
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InChI
InChI=1S/C28H36N4O2/c1-31(17-18-33)22-11-12-25-24(19-22)28(30-27(29-25)21-7-3-4-8-21)32-15-13-20(14-16-32)23-9-5-6-10-26(23)34-2/h5-6,9-12,19-21,33H,3-4,7-8,13-18H2,1-2H3
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InChIKey
SMTIKJXXHINZME-UHFFFAOYSA-N
Physicochemical Property
logP
5.1085
Rotatable Bonds
7
Heavy Atom Count
34
Polar Areas
61.72
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118610255
ChEMBL ID
CHEMBL4437603
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02429, Neurotensin receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 3880 nM
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