General Information of the Compound
Compound ID
CP0396325
Compound Name
N-[(2R,3S)-1-[2-acetyl-5-[(dimethylamino)methyl]anilino]-3-(1H-indol-3-yl)-1-oxobutan-2-yl]-4-(2-methylpropanoyl)piperidine-1-carboxamide
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Structure
Formula
C33H43N5O4
Molecular Weight
573.738
Canonical SMILES
CC(C)C(=O)C1CCN(CC1)C(=O)N[C@H]([C@@H](C)c1c[nH]c2ccccc12)C(=O)Nc1cc(CN(C)C)ccc1C(C)=O
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InChI
InChI=1S/C33H43N5O4/c1-20(2)31(40)24-13-15-38(16-14-24)33(42)36-30(21(3)27-18-34-28-10-8-7-9-26(27)28)32(41)35-29-17-23(19-37(5)6)11-12-25(29)22(4)39/h7-12,17-18,20-21,24,30,34H,13-16,19H2,1-6H3,(H,35,41)(H,36,42)/t21-,30+/m0/s1
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InChIKey
UQWKQQRBMYBEPJ-URAOTHONSA-N
Physicochemical Property
logP
5.1896
Rotatable Bonds
10
Heavy Atom Count
42
Polar Areas
114.61
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
5
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 145974145
ChEMBL ID
CHEMBL4215052
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01505, Somatostatin receptor type 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000389 CHO-DXB11 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 2 nM
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