General Information of the Compound
Compound ID
CP0394717
Compound Name
5-methyl-3-phenyl-N-(3-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylpropyl)-1,2-oxazole-4-carboxamide
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Structure
Formula
C27H31N3O2
Molecular Weight
429.564
Canonical SMILES
Cc1onc(c1C(=O)NCCCN1CCC2(CCc3ccccc23)CC1)-c1ccccc1
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InChI
InChI=1S/C27H31N3O2/c1-20-24(25(29-32-20)22-9-3-2-4-10-22)26(31)28-16-7-17-30-18-14-27(15-19-30)13-12-21-8-5-6-11-23(21)27/h2-6,8-11H,7,12-19H2,1H3,(H,28,31)
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InChIKey
SGSDMRAOGDTNHU-UHFFFAOYSA-N
Physicochemical Property
logP
4.74992
Rotatable Bonds
6
Heavy Atom Count
32
Polar Areas
58.37
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44407066
ChEMBL ID
CHEMBL381507
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 1000 nM
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   LI
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   TS