General Information of the Compound
Compound ID
CP0394387
Compound Name
N-[6-[3-(4-methoxybenzoyl)-1-(oxan-4-ylmethyl)indol-7-yl]oxyhexyl]acetamide
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Structure
Formula
C30H38N2O5
Molecular Weight
506.643
Canonical SMILES
COc1ccc(cc1)C(=O)c1cn(CC2CCOCC2)c2c(OCCCCCCNC(C)=O)cccc12
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InChI
InChI=1S/C30H38N2O5/c1-22(33)31-16-5-3-4-6-17-37-28-9-7-8-26-27(30(34)24-10-12-25(35-2)13-11-24)21-32(29(26)28)20-23-14-18-36-19-15-23/h7-13,21,23H,3-6,14-20H2,1-2H3,(H,31,33)
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InChIKey
LPGRJOFVSNBPMQ-UHFFFAOYSA-N
Physicochemical Property
logP
5.3828
Rotatable Bonds
13
Heavy Atom Count
37
Polar Areas
78.79
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 145993892
ChEMBL ID
CHEMBL4294653
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01298, Cannabinoid receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 3918 nM
   TI
   LI
   LO
   TS
Protein ID: PT00834, Cannabinoid receptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
2
Ki = 1969 nM
   TI
   LI
   LO
   TS