General Information of the Compound
Compound ID
CP0394103
Compound Name
N-hydroxy-4-iodobenzamide
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Synonyms
2593-31-9
4-Iodobenzohydroximic acid
AC1LDBQC
AC1Q7DII
AKOS008969031
BDBM50015131
CHEMBL155287
CTK8A6787
EN300-53710
HXIKIQLHKIBCOH-UHFFFAOYSA-N
MCULE-3184298763
MolPort-005-220-499
N-Hydroxy-4-iodo-benzamide
N-Hydroxy-4-iodobenzamide
N-Hydroxy-4-iodobenzamide #
NE46453
ZINC20303936
p-Iodobenzohydroxamic acid
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Structure
Formula
C7H6INO2
Molecular Weight
263.034
Canonical SMILES
ONC(=O)c1ccc(I)cc1
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InChI
InChI=1S/C7H6INO2/c8-6-3-1-5(2-4-6)7(10)9-11/h1-4,11H,(H,9,10)
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InChIKey
HXIKIQLHKIBCOH-UHFFFAOYSA-N
Physicochemical Property
logP
1.4102
Rotatable Bonds
1
Heavy Atom Count
11
Polar Areas
49.33
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Complexity
11

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 615643
ChEMBL ID
CHEMBL155287
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01743, Polyunsaturated fatty acid 5-lipoxygenase
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000194 RBL-1
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
IC50 = 15000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( N-Hydroxy-4-iodo-benzamide )
Drug Name N-Hydroxy-4-iodo-benzamide
Target(s)
Arachidonate 5-lipoxygenase (5-LOX)
 Target Info 
Inhibitor