General Information of the Compound
Compound ID
CP0393761
Compound Name
(2S,3S,4R,5R)-3,4-dihydroxy-N-methyl-5-[6-(naphthalen-2-ylmethylamino)purin-9-yl]selenolane-2-carboxamide
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Structure
Formula
C22H22N6O3Se
Molecular Weight
497.417
Canonical SMILES
CNC(=O)[C@H]1[Se][C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3ccc4ccccc4c3)ncnc12
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InChI
InChI=1S/C22H22N6O3Se/c1-23-21(31)18-16(29)17(30)22(32-18)28-11-27-15-19(25-10-26-20(15)28)24-9-12-6-7-13-4-2-3-5-14(13)8-12/h2-8,10-11,16-18,22,29-30H,9H2,1H3,(H,23,31)(H,24,25,26)/t16-,17+,18-,22+/m0/s1
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InChIKey
IYLDAMOUTMJQCF-RQXXJAGISA-N
Physicochemical Property
logP
1.0643
Rotatable Bonds
5
Heavy Atom Count
32
Polar Areas
125.19
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
8
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 137657589
ChEMBL ID
CHEMBL4103146
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00840, Adenosine receptor A1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 440 nM
   TI
   LI
   LO
   TS
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 195 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1.76 nM
   TI
   LI
   LO
   TS