General Information of the Compound
Compound ID
CP0392752
Compound Name
(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-aminobenzoyl)amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
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Structure
Formula
C79H120N26O19
Molecular Weight
1737.992
Canonical SMILES
CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)c1ccccc1N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O
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InChI
InChI=1S/C79H120N26O19/c1-39(2)31-54(98-70(117)56(33-43-18-22-46(107)23-19-43)100-71(118)57(35-45-37-89-38-93-45)101-66(113)50(15-10-28-90-77(83)84)94-64(111)48-13-8-9-14-49(48)80)69(116)102-58(36-61(82)110)72(119)99-55(32-40(3)4)73(120)104-62(41(5)6)74(121)105-63(42(7)106)75(122)97-52(17-12-30-92-79(87)88)65(112)96-53(26-27-60(81)109)68(115)95-51(16-11-29-91-78(85)86)67(114)103-59(76(123)124)34-44-20-24-47(108)25-21-44/h8-9,13-14,18-25,37-42,50-59,62-63,106-108H,10-12,15-17,26-36,80H2,1-7H3,(H2,81,109)(H2,82,110)(H,89,93)(H,94,111)(H,95,115)(H,96,112)(H,97,122)(H,98,117)(H,99,119)(H,100,118)(H,101,113)(H,102,116)(H,103,114)(H,104,120)(H,105,121)(H,123,124)(H4,83,84,90)(H4,85,86,91)(H4,87,88,92)/t42-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,62+,63+/m1/s1
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InChIKey
KOFSEBGXKJTRQA-DVERMALCSA-N
Physicochemical Property
logP
-5.29329
Rotatable Bonds
54
Heavy Atom Count
124
Polar Areas
773.77
Hydrogen Bond Donor Count
29
Hydrogen Bond Acceptor Count
23
Complexity
124

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 145979291
ChEMBL ID
CHEMBL4282168
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02259, Neuropeptide Y receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01909, Neuropeptide Y receptor type 4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS