General Information of the Compound
| Compound ID |
CP0392286
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
8''-chloro-5''-(2-methylaminoethoxy)spiro[cyclohexane-1,4''-(1'',2'',3'',4''-tetrahydroquinazoline)]-2''-one
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C16H22ClN3O2
|
||||||||||||||||||
| Molecular Weight |
323.824
|
||||||||||||||||||
| Canonical SMILES |
CNCCOc1ccc(Cl)c2NC(=O)NC3(CCCCC3)c12
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C16H22ClN3O2/c1-18-9-10-22-12-6-5-11(17)14-13(12)16(20-15(21)19-14)7-3-2-4-8-16/h5-6,18H,2-4,7-10H2,1H3,(H2,19,20,21)
Show/Hide
|
||||||||||||||||||
| InChIKey |
UQZKFTSBRMZGHX-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01538, 3',5'-cyclic-AMP phosphodiesterase 4D
Protein ID: PT01728, High affinity 3',5'-cyclic-AMP phosphodiesterase 7A