General Information of the Compound
Compound ID
CP0392119
Compound Name
5-Chloro-2-methyl-3-(8-methyl-8-aza-bicyclo[3.2.1]oct-2-en-3-yl)-1H-indole
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Structure
Formula
C17H19ClN2
Molecular Weight
286.806
Canonical SMILES
CN1C2CCC1C=C(C2)c1c(C)[nH]c2ccc(Cl)cc12
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InChI
InChI=1S/C17H19ClN2/c1-10-17(15-9-12(18)3-6-16(15)19-10)11-7-13-4-5-14(8-11)20(13)2/h3,6-7,9,13-14,19H,4-5,8H2,1-2H3
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InChIKey
MVLIQLIRDXPWKN-UHFFFAOYSA-N
Physicochemical Property
logP
4.37962
Rotatable Bonds
1
Heavy Atom Count
20
Polar Areas
19.03
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
1
Complexity
20

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44403351
ChEMBL ID
CHEMBL363417
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 40 nM
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