General Information of the Compound
Compound ID
CP0391017
Compound Name
2-(3-(4-chlorophenethyl)-1,2,4-oxadiazol-5-yl)-4-(4-methylpiperazin-1-yl)-1H-pyrrolo[2,3-b]pyridine
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Structure
Formula
C22H23ClN6O
Molecular Weight
422.92
Canonical SMILES
CN1CCN(CC1)c1ccnc2[nH]c(cc12)-c1nc(CCc2ccc(Cl)cc2)no1
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InChI
InChI=1S/C22H23ClN6O/c1-28-10-12-29(13-11-28)19-8-9-24-21-17(19)14-18(25-21)22-26-20(27-30-22)7-4-15-2-5-16(23)6-3-15/h2-3,5-6,8-9,14H,4,7,10-13H2,1H3,(H,24,25)
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InChIKey
YEVWQKVDQWPJNY-UHFFFAOYSA-N
Physicochemical Property
logP
3.8033
Rotatable Bonds
5
Heavy Atom Count
30
Polar Areas
74.08
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 136043787
ChEMBL ID
CHEMBL211402
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 1000 nM
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