General Information of the Compound
Compound ID
CP0390128
Compound Name
[(3S,8S,9R,10R,12R,13S,14R,17S)-17-acetyl-3-(2-chloroacetyl)oxy-8,14,17-trihydroxy-10,13-dimethyl-1,2,3,4,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-12-yl] 4-hydroxybenzoate
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Structure
Formula
C30H37ClO9
Molecular Weight
577.07
Canonical SMILES
CC(=O)[C@]1(O)CC[C@@]2(O)[C@]1(C)[C@@H](C[C@@H]1[C@@]3(C)CC[C@@H](CC3=CC[C@@]21O)OC(=O)CCl)OC(=O)c1ccc(O)cc1
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InChI
InChI=1S/C30H37ClO9/c1-17(32)28(36)12-13-30(38)27(28,3)23(40-25(35)18-4-6-20(33)7-5-18)15-22-26(2)10-9-21(39-24(34)16-31)14-19(26)8-11-29(22,30)37/h4-8,21-23,33,36-38H,9-16H2,1-3H3/t21-,22+,23+,26-,27+,28+,29-,30+/m0/s1
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InChIKey
UCHSQXQNUUFFLM-CZTKLRHSSA-N
Physicochemical Property
logP
3.1908
Rotatable Bonds
5
Heavy Atom Count
40
Polar Areas
150.59
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
9
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 132502975
ChEMBL ID
CHEMBL4068115
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03343, Toll-like receptor 4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000192 AD-293 Homo sapiens (Human)  1
1
EC50 = 3270 nM
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