General Information of the Compound
Compound ID
CP0387589
Compound Name
[3-[6-[3-[2-acetamidoethyl(methyl)amino]phenoxy]hexoxy]phenyl] N-cyclohexylcarbamate
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Structure
Formula
C30H43N3O5
Molecular Weight
525.69
Canonical SMILES
CN(CCNC(C)=O)c1cccc(OCCCCCCOc2cccc(OC(=O)NC3CCCCC3)c2)c1
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InChI
InChI=1S/C30H43N3O5/c1-24(34)31-18-19-33(2)26-14-10-15-27(22-26)36-20-8-3-4-9-21-37-28-16-11-17-29(23-28)38-30(35)32-25-12-6-5-7-13-25/h10-11,14-17,22-23,25H,3-9,12-13,18-21H2,1-2H3,(H,31,34)(H,32,35)
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InChIKey
KCUHFUCEFBESAA-UHFFFAOYSA-N
Physicochemical Property
logP
5.6982
Rotatable Bonds
15
Heavy Atom Count
38
Polar Areas
89.13
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
38

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 145976375
ChEMBL ID
CHEMBL4206000
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01843, Melatonin receptor type 1A
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
Ki = 27.54 nM
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   LI
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   TS
Protein ID: PT02174, Melatonin receptor type 1B
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
Ki = 295.12 nM
   TI
   LI
   LO
   TS