General Information of the Compound
Compound ID
CP0384881
Compound Name
N-[[2-(azocan-1-yl)-4-(trifluoromethyl)phenyl]methyl]-2-[3-fluoro-4-(methanesulfonamido)phenyl]propanamide
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Structure
Formula
C25H31F4N3O3S
Molecular Weight
529.6
Canonical SMILES
CC(C(=O)NCc1ccc(cc1N1CCCCCCC1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1
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InChI
InChI=1S/C25H31F4N3O3S/c1-17(18-9-11-22(21(26)14-18)31-36(2,34)35)24(33)30-16-19-8-10-20(25(27,28)29)15-23(19)32-12-6-4-3-5-7-13-32/h8-11,14-15,17,31H,3-7,12-13,16H2,1-2H3,(H,30,33)
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InChIKey
AIQNUCNHLLCWSW-UHFFFAOYSA-N
Physicochemical Property
logP
5.4064
Rotatable Bonds
7
Heavy Atom Count
36
Polar Areas
78.51
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 58873283
ChEMBL ID
CHEMBL3629490
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02183, Transient receptor potential cation channel subfamily V member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2.8 nM
   TI
   LI
   LO
   TS