General Information of the Compound
Compound ID
CP0383412
Compound Name
1-benzyl-4-phenylpiperidin-4-ol
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Synonyms
1-Benzyl-4-phenyl-4-piperidinol
1-Benzyl-4-phenyl-piperidin-4-ol
1-Benzyl-4-phenylpiperidin-4-ol
1-benzyl-4-hydroxy-4-phenyl piperidine
1-benzyl-4-hydroxy-4-phenylpiperidine
1-benzyl-4-phenylpiperidin-4-ol
4-Piperidinol, 1-benzyl-4-phenyl-
63843-83-4
AC1L3YAO
AC1Q7B56
AKOS000541462
ANW-45516
BCP13431
BDBM50210409
BRN 0235839
CHEMBL230141
CTK5B9985
DTXSID60213290
EINECS 264-512-8
F1446-0078
FCLMXEAPEVBCKQ-UHFFFAOYSA-N
HMS1672E06
MolPort-001-954-320
NSC116051
Oprea1_173104
Oprea1_213406
SCHEMBL1411499
STK081775
ZINC320034
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Structure
Formula
C18H21NO
Molecular Weight
267.372
Canonical SMILES
OC1(CCN(Cc2ccccc2)CC1)c1ccccc1
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InChI
InChI=1S/C18H21NO/c20-18(17-9-5-2-6-10-17)11-13-19(14-12-18)15-16-7-3-1-4-8-16/h1-10,20H,11-15H2
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InChIKey
FCLMXEAPEVBCKQ-UHFFFAOYSA-N
CAS
63843-83-4
Physicochemical Property
logP
3.1702
Rotatable Bonds
3
Heavy Atom Count
20
Polar Areas
23.47
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
20

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 97333
SID: 15962143
ChEMBL ID
CHEMBL230141
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 1983 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( 1-benzyl-4-phenylpiperidin-4-ol )
Drug Name 1-benzyl-4-phenylpiperidin-4-ol
Target(s)
Nociceptin receptor (OPRL1)
 Target Info 
Inhibitor