General Information of the Compound
Compound ID
CP0381778
Compound Name
(5S)-5-(naphthalen-1-ylmethyl)-1-(4-phenylbut-3-ynyl)-3-(2-pyrrolidin-1-ylethyl)imidazolidine-2,4-dione
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Structure
Formula
C30H31N3O2
Molecular Weight
465.597
Canonical SMILES
O=C1[C@H](Cc2cccc3ccccc23)N(CCC#Cc2ccccc2)C(=O)N1CCN1CCCC1
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InChI
InChI=1S/C30H31N3O2/c34-29-28(23-26-16-10-15-25-14-4-5-17-27(25)26)32(20-7-6-13-24-11-2-1-3-12-24)30(35)33(29)22-21-31-18-8-9-19-31/h1-5,10-12,14-17,28H,7-9,18-23H2/t28-/m0/s1
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InChIKey
HJMMYRQSVYVNHK-NDEPHWFRSA-N
Physicochemical Property
logP
4.5527
Rotatable Bonds
7
Heavy Atom Count
35
Polar Areas
43.86
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44345936
ChEMBL ID
CHEMBL324511
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01196, Somatostatin receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 398.11 nM
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