General Information of the Compound
| Compound ID |
CP0380897
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| Compound Name |
2-[(6-ethoxy-4-methylquinazolin-2-yl)amino]-4-methyl-1H-pyrimidin-6-one
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| Structure |
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| Formula |
C16H17N5O2
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| Molecular Weight |
311.345
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| Canonical SMILES |
CCOc1ccc2nc(Nc3nc(=O)cc(C)[nH]3)nc(C)c2c1
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| InChI |
InChI=1S/C16H17N5O2/c1-4-23-11-5-6-13-12(8-11)10(3)18-16(19-13)21-15-17-9(2)7-14(22)20-15/h5-8H,4H2,1-3H3,(H2,17,18,19,20,21,22)
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| InChIKey |
QEMQLVAVCMAJBF-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02212, Signal transducer and activator of transcription 1-alpha/beta
Protein ID: PT01503, Signal transducer and activator of transcription 3