General Information of the Compound
| Compound ID |
CP0377396
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| Compound Name |
N-(2,6-difluorophenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-2-phenylacetamide
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| Structure |
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| Formula |
C25H24F2N2O2
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| Molecular Weight |
422.475
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| Canonical SMILES |
OC1(CCN(CC1)C(C(=O)Nc1c(F)cccc1F)c1ccccc1)c1ccccc1
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| InChI |
InChI=1S/C25H24F2N2O2/c26-20-12-7-13-21(27)22(20)28-24(30)23(18-8-3-1-4-9-18)29-16-14-25(31,15-17-29)19-10-5-2-6-11-19/h1-13,23,31H,14-17H2,(H,28,30)
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| InChIKey |
ZAXWEHCCAIIFBR-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01200, Delta-type opioid receptor
Protein ID: PT00983, Kappa-type opioid receptor
Protein ID: PT01515, Mu-type opioid receptor
Protein ID: PT01360, Nociceptin receptor