General Information of the Compound
Compound ID
CP0377146
Compound Name
N-(1-adamantyl)-5-[4-[3-(morpholin-4-ylmethyl)phenyl]phenyl]-1,2-oxazole-3-carboxamide
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Structure
Formula
C31H35N3O3
Molecular Weight
497.639
Canonical SMILES
O=C(NC12CC3CC(CC(C3)C1)C2)c1cc(on1)-c1ccc(cc1)-c1cccc(CN2CCOCC2)c1
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InChI
InChI=1S/C31H35N3O3/c35-30(32-31-17-22-12-23(18-31)14-24(13-22)19-31)28-16-29(37-33-28)26-6-4-25(5-7-26)27-3-1-2-21(15-27)20-34-8-10-36-11-9-34/h1-7,15-16,22-24H,8-14,17-20H2,(H,32,35)
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InChIKey
JLPMHXQQTLQZIM-UHFFFAOYSA-N
Physicochemical Property
logP
5.5394
Rotatable Bonds
6
Heavy Atom Count
37
Polar Areas
67.6
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 127047564
ChEMBL ID
CHEMBL3799982
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01099, Fatty-acid amide hydrolase 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 830 nM
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