General Information of the Compound
Compound ID
CP0374952
Compound Name
2-[4-[6-(3-ethoxyphenyl)-3-methyl-6-bicyclo[3.1.0]hexanyl]piperazin-1-yl]-1,3,5-triazine
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Structure
Formula
C22H29N5O
Molecular Weight
379.508
Canonical SMILES
CCOc1cccc(c1)C1(C2CC(C)CC12)N1CCN(CC1)c1ncncn1
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InChI
InChI=1S/C22H29N5O/c1-3-28-18-6-4-5-17(13-18)22(19-11-16(2)12-20(19)22)27-9-7-26(8-10-27)21-24-14-23-15-25-21/h4-6,13-16,19-20H,3,7-12H2,1-2H3
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InChIKey
ANPFSBYUHWCSQO-UHFFFAOYSA-N
Physicochemical Property
logP
2.9637
Rotatable Bonds
5
Heavy Atom Count
28
Polar Areas
54.38
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 73353531
ChEMBL ID
CHEMBL2397293
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02259, Neuropeptide Y receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
IC50 = 4270 nM
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