General Information of the Compound
Compound ID
CP0373612
Compound Name
5-(Dimethylamino)-N-(5-(dimethylamino)naphthalen-1-ylsulfonyl)-N-(4-methoxy-3-(piperazin-1-yl)phenyl)naphthalene-1-sulfonamide
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Structure
Formula
C35H39N5O5S2
Molecular Weight
673.861
Canonical SMILES
COc1ccc(cc1N1CCNCC1)N(S(=O)(=O)c1cccc2c(cccc12)N(C)C)S(=O)(=O)c1cccc2c(cccc12)N(C)C
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InChI
InChI=1S/C35H39N5O5S2/c1-37(2)30-14-6-12-28-26(30)10-8-16-34(28)46(41,42)40(25-18-19-33(45-5)32(24-25)39-22-20-36-21-23-39)47(43,44)35-17-9-11-27-29(35)13-7-15-31(27)38(3)4/h6-19,24,36H,20-23H2,1-5H3
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InChIKey
NPEAGLGRRKGAOK-UHFFFAOYSA-N
Physicochemical Property
logP
5.1274
Rotatable Bonds
9
Heavy Atom Count
47
Polar Areas
102.5
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
9
Complexity
47

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49781250
SID: 103055330
ChEMBL ID
CHEMBL1256256
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 135 nM
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