General Information of the Compound
Compound ID
CP0372351
Compound Name
2,2-diphenyl-N-(3-phenylpropyl)acetamide
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Synonyms
2,2-diphenyl-N-(3-phenylpropyl)acetamide
AC1M5U8J
AKOS001062446
BDBM50263151
CHEMBL476336
MCULE-9627491940
MolPort-003-249-505
N-(3-Phenyl)propyl-2,2-diphenylacetamide
N-(3-Phenylpropyl)-2,2-diphenylacetamide
ST50913753
STK437441
Z26437312
ZINC3269206
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Structure
Formula
C23H23NO
Molecular Weight
329.443
Canonical SMILES
O=C(NCCCc1ccccc1)C(c1ccccc1)c1ccccc1
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InChI
InChI=1S/C23H23NO/c25-23(24-18-10-13-19-11-4-1-5-12-19)22(20-14-6-2-7-15-20)21-16-8-3-9-17-21/h1-9,11-12,14-17,22H,10,13,18H2,(H,24,25)
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InChIKey
GGASESVHBWYDKY-UHFFFAOYSA-N
Physicochemical Property
logP
4.5675
Rotatable Bonds
7
Heavy Atom Count
25
Polar Areas
29.1
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
1
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 2385541
ChEMBL ID
CHEMBL476336
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01298, Cannabinoid receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 3400 nM
   TI
   LI
   LO
   TS
Protein ID: PT00834, Cannabinoid receptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 7900 nM
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( N-(3-Phenyl)propyl-2,2-diphenylacetamide )
Drug Name N-(3-Phenyl)propyl-2,2-diphenylacetamide
Target(s)
Cannabinoid receptor 1 (CB1)
Inhibitor