General Information of the Compound
Compound ID
CP0372317
Compound Name
(+/-)-N,2-bis(2,6-dimethylphenyl)-4-methoxy-N-methyl-5,6,7,8-tetrahydroquinolin-5-amine
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Structure
Formula
C27H32N2O
Molecular Weight
400.566
Canonical SMILES
COc1cc(nc2CCCC(N(C)c3c(C)cccc3C)c12)-c1c(C)cccc1C
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InChI
InChI=1S/C27H32N2O/c1-17-10-7-11-18(2)25(17)22-16-24(30-6)26-21(28-22)14-9-15-23(26)29(5)27-19(3)12-8-13-20(27)4/h7-8,10-13,16,23H,9,14-15H2,1-6H3
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InChIKey
RSGJNMHEDWRJJK-UHFFFAOYSA-N
Physicochemical Property
logP
6.50468
Rotatable Bonds
4
Heavy Atom Count
30
Polar Areas
25.36
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44567970
ChEMBL ID
CHEMBL479766
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02772, C5a anaphylatoxin chemotactic receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS