General Information of the Compound
| Compound ID |
CP0353892
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| Compound Name |
JNJ-18038683
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| Synonyms |
5-HT 7 antagonist (depression), Johnson & Johnson
JNJ-18038683
Serotonin 7 antagonist (depression), Johnson & Johnson
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| Structure |
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| Formula |
C20H20ClN3
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| Molecular Weight |
337.854
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| Canonical SMILES |
Clc1ccc(cc1)-c1nn(Cc2ccccc2)c2CCNCCc12
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| InChI |
InChI=1S/C20H20ClN3/c21-17-8-6-16(7-9-17)20-18-10-12-22-13-11-19(18)24(23-20)14-15-4-2-1-3-5-15/h1-9,22H,10-14H2
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| InChIKey |
UKJPMZGILXATGT-UHFFFAOYSA-N
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| CAS |
851373-91-6
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound