General Information of the Compound
| Compound ID |
CP0318933
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| Compound Name |
US9238644, 15
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| Structure |
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| Formula |
C26H29ClN6O
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| Molecular Weight |
477.012
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| Canonical SMILES |
NC(=O)C1(CC1)c1ccccc1CCc1nc(Nc2ccc(nc2)C2CCNCC2)ncc1Cl
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| InChI |
InChI=1S/C26H29ClN6O/c27-21-16-31-25(32-19-6-8-22(30-15-19)18-9-13-29-14-10-18)33-23(21)7-5-17-3-1-2-4-20(17)26(11-12-26)24(28)34/h1-4,6,8,15-16,18,29H,5,7,9-14H2,(H2,28,34)(H,31,32,33)
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| InChIKey |
YNPZQOCKZKZHEM-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00864, Vascular endothelial growth factor receptor 2
Protein ID: PT00925, Vascular endothelial growth factor receptor 3