General Information of the Compound
| Compound ID |
CP0314616
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| Compound Name |
US9238644, 21
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| Structure |
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| Formula |
C24H28ClN7O
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| Molecular Weight |
465.989
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| Canonical SMILES |
CN1CCC(C1)n1cc(Nc2ncc(Cl)c(CCc3ccccc3C3(CC3)C(N)=O)n2)cn1
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| InChI |
InChI=1S/C24H28ClN7O/c1-31-11-8-18(15-31)32-14-17(12-28-32)29-23-27-13-20(25)21(30-23)7-6-16-4-2-3-5-19(16)24(9-10-24)22(26)33/h2-5,12-14,18H,6-11,15H2,1H3,(H2,26,33)(H,27,29,30)
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| InChIKey |
IZRLUPFLGZEWCW-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00864, Vascular endothelial growth factor receptor 2
Protein ID: PT00925, Vascular endothelial growth factor receptor 3