General Information of the Compound
| Compound ID |
CP0313365
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| Compound Name |
US9238644, 6
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| Structure |
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| Formula |
C21H20ClN5O
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| Molecular Weight |
393.878
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| Canonical SMILES |
NC(=O)C1(CC1)c1ccccc1CCc1nc(Nc2cccnc2)ncc1Cl
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| InChI |
InChI=1S/C21H20ClN5O/c22-17-13-25-20(26-15-5-3-11-24-12-15)27-18(17)8-7-14-4-1-2-6-16(14)21(9-10-21)19(23)28/h1-6,11-13H,7-10H2,(H2,23,28)(H,25,26,27)
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| InChIKey |
IALBGKOBFXRYIF-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00864, Vascular endothelial growth factor receptor 2
Protein ID: PT00925, Vascular endothelial growth factor receptor 3