General Information of the Compound
Compound ID
CP0304865
Compound Name
(2S)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-(6-methoxynaphthalen-2-yl)propanamide
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Structure
Formula
C24H24N2O3
Molecular Weight
388.467
Canonical SMILES
COc1ccc2cc(ccc2c1)[C@H](C)C(=O)NCCc1c[nH]c2ccc(O)cc12
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InChI
InChI=1S/C24H24N2O3/c1-15(16-3-4-18-12-21(29-2)7-5-17(18)11-16)24(28)25-10-9-19-14-26-23-8-6-20(27)13-22(19)23/h3-8,11-15,26-27H,9-10H2,1-2H3,(H,25,28)/t15-/m0/s1
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InChIKey
IITIMUIBPPQZLN-HNNXBMFYSA-N
Physicochemical Property
logP
4.4977
Rotatable Bonds
6
Heavy Atom Count
29
Polar Areas
74.35
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118723547
ChEMBL ID
CHEMBL3359451
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02183, Transient receptor potential cation channel subfamily V member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000612 BEAS-2B Homo sapiens (Human)  1
1
IC50 = 13000 nM
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